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Table 3 Groups × genotypes ANOVA of ALFF

From: Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment

Brain region

BA

Peak MNI coordinates (mm)

Peak F value

Cluster size

  

x

y

z

  

(1) Main effect of groups

L inferior frontal gyrus/superior temporal lobe/middle temporal lobe

22/38/45

−57

21

21

26.78

23841

R calcarine/precuneus/cerebellum posterior lobe

7/18

6

−63

−18

12.27

15120

(2) Main effect of genotypes

L middle frontal gyrus/inferior frontal gyrus

9/45

−57

21

18

19.53

13851

R medial frontal gyrus/superior frontal gyrus/ anterior cingulum

10

6

63

6

12.88

13608

(3) Groups × genotypes interaction

L superior frontal gyrus/middle frontal gyrus/ medial frontal gyrus/R anterior cingulum

9/32/46

−54

27

21

13.14

19278

L middle occipital lobe/cuneus/precuneus

19

−21

−96

24

9.34

10557

B cerebellum posterior lobe

—

−24

−60

−24

8.56

18468

  1. Note: a corrected threshold by Monte Carlo stimulation at P <0.05. Cluster size is in mm3. BA, Brodmann's area; B, bilateral; L, left; MNI. Montreal Neurological Institute; R, right.