Sevoflurane reduces glial activation in cerebellum of experimental autoimmune encephalomyelitis (EAE) mice. Representative sagittal sections from (A) oxygen-treated and (B) sevoflurane-treated mice were stained with antibody to glial fibrillary acidic protein (GFAP) to detect activated astrocytes. (C) The total GFAP+ staining per field of view was quantified. Data are mean ± SEM of n = 6 sections per animal, three mice per group; *P <0.05 versus oxygen. WM, white matter; BG, Bergmann glia.