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Scheme 1 | Journal of Neuroinflammation

Scheme 1

From: Susceptibility of juvenile and adult blood–brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity

Scheme 1

An illustration of the experimental design. 1. Verification of intracerebroventricular (icv) stereotaxic coordinates. 2. Blood–brain barrier (BBB) integrity assessment. 3. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) expression measurement. 4. P-gp and BCRP transport activity measurement. 5. Glial activation evaluation by glial fibrillary acid protein (GFAP) immunohistochemistry. 6. Brain and serum cytokines/chemokines quantification.

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Journal of Neuroinflammation

ISSN: 1742-2094