Neurological function determined by rotating pole test and spontaneous behavior. (A) Rotating pole scores for sham-operated rats, rats with induced subarachnoid hemorrhage (SAH) treated with vehicle and rats induced SAH treated with U0126 at 6 h, 12 h and 24 h after SAH. Scores were obtained at day 3 after SAH with the pole either kept still (no rotation) or rotating at 3 rpm or 10 rpm. (B,C) Spontaneous activity of rats placed in a clean test cage for a 20 minutes observation period at day 3 after SAH for sham rats and SAH rats treated with vehicle or U0126 at 6 h, 12 h and 24 h after SAH. (B) Time spent with rearing. (C) Time spent sitting or lying at the same place (no movement). Data are expressed as mean ± SEM, n = 5 in each group. * Indicates significant differences as compared to sham-operated rats, # indicates significant differences as compared to the SAH group; */#
P <0.05, **/##
P <0.01 and ***P <0.001.