Figure 4From: DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP) Clinical course of actively induced in HLA-DQB1*0602 Tg mice. EAE was induced by the indicated PLP peptide in CFA as described in methods (protocol 2): Pertussis toxin was administered immediately and 48 h after immunization. The mice received an identical booster immunization with PLP peptide in CFA on the flank one week later. I, incidence.Back to article page