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Figure 6 | Journal of Neuroinflammation

Figure 6

From: DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP)

Figure 6

Histopathology of PLP-induced EAE in HLA DQB1*0602 Tg mouse. Samples were taken on day19 after immunization. Panel (A) shows the spinal cord, (B) the cerebellum and (C) the optic nerve. The sections were stained with hematoxylin & eosin (a), Luxol fast blue for myelin. (b) Bieschowsky silver impregnation for axons (c) and by immunocytochemistry for CD3 (d), and Mac-3 (e). Note the unusually profound inflammation in the cortex and optic nerve. Original magnifications: A and B: × 25; C: × 100.

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Journal of Neuroinflammation

ISSN: 1742-2094