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Table 2 Fold change of mRNA levels of inflammatory mediators incorpus callosum and cerebellum of 6-week-old Nestin-Pex5 mice

From: Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system

Nestin-Pex5 6 weeks
Fold change Corpus callosum Cerebellum
TNFα 28.96 ± 6.27*** 17.15 ± 8.85
C1q 8.40 ± 1.43*** 2.94 ± 1.45
TLR2 11.91 ± 3.26*** 12.42 ± 6.10
Mpeg1 13.64 ± 6.38*** 10.63 ± 0.34***
TGFβ 2.83 ± 0.18*** 3.38 ± 0.5**
IL10 30.92 ± 10.65* 3.18 ± 3.10
Arg1 1.78 ± 0.08** 2.78 ± 1.11
Fizz1 13.31 ± 8.59 1.62 ± 0.50
  1. Values represent means of 4 independent samples. * p < 0.05, ** p < 0.01, *** p < 0.001. Expression levels were normalized to β-actin expression.