Figure 6
From: The NAMPT inhibitor FK866 reverts the damage in spinal cord injury
Effects of FK866 on Bax expression. By western blot and immunohistochemical analysis Bax levels were evaluated. Spinal cord obtained from SCI-operated mice exhibited appreciably increased Bax levels (a, a1 and c). FK866 (a, a1 and d) treatment prevented the SCI-induced Bax expression. The relative expression of the protein bands was standardized for densitometric analysis to β-actin levels, reported in panel a, a1 and are expressed as mean ± S.E.M from n = 5/6 spinal cord for each group. **p < 0.001 vs sham, °°p < 0.001 vs SCI + vehicle.