Figure 5

Effect of BBG, OxATP and A-438079 on I/R -induced IL-1ß, TNF-α and IL-6 overexperession. Steady-state mRNA expression for IL-1ß (A), TNF-α (B) and IL-6 (C) quantified by real-time RT-PCR. Expression is relative to GAPDH. Values are expressed as the mean ± S.E.M. **P < 0.01 versus saline group; ##P < 0.01 versus sham group (n = 7 in all the groups). BBG, Brilliant blue G; GAPHD, glyceraldehyde-3-phosphate dehydrogenase; IL-1ß, interleukin-1ß; IL-6, interleukin-6; I/R, ischemia/reperfusion; OxATP, adenosine 5′-triphosphate-2′,3′-dialdehyde; S.E.M., standard error of the mean; TNF-α, tumor necrosis factor α.