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Table 1 Variables evaluated in the open field experiment and compared within the multivariate analyses

From: Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury

Total arena

Centre zonea

Average velocity (cm/second)

Velocity (cm/second)

Track length (cm)

Track length (cm)

Activity (%) (velocity of >0.5 pixels/second or occurrences of head stretches/bobs and tail moves)

Activity (%)

Ambulation (accelerations from stationary to <0.5 pixels/second)

Ambulation

Speed moved in field (0 to 1 cm/minute)

Visits

Speed moved in field (1 to 4 cm/minute)

Visit latencies

Speed moved in field (4 to 10 cm/minute)

Durations

 

Head bobs

 

Head stretches

 

Tail moves

 

Number of zone crossings

 

Number of rated zone crossings

  1. aThe centre zone was defined as lying 5 cm or more from the arena edge.