Figure 1From: Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice A) Representative images of the dentate gyrus of hippocampus showing immunoreactivity for Iba1. A) Non-stressed female treated with vehicle; B) Prenatally stressed female treated with vehicle; C) Non-stressed female treated with LPS and D) Prenatally stressed female treated with LPS. Inserts show details of the morphology of Iba1-immunoreactive cells at high magnification. Scale bar, 50 μm. In the inserts, the scale bar represents 7.5 μm. B) Number of Iba1-immunoreactive cells/mm3 in the hilus of dentate gyrus of hippocampus. NS, non-stressed female mice; PS, prenatally stressed females. Filled bars, animals treated with vehicle (VEH). Empty bars, animals treated with LPS. Data are mean ± SEM. *, Significant differences (P <0.05) versus NS-VEH. aSignificant difference (P <0.05) versus NS-VEH and PS-VEH mice. bbSignificant difference (P <0.01) versus NS-VEH and PS-LPS. Back to article page