Figure 1

Cell morphology, myelin basic protein, and glial fibrillary acidic protein expression in MO3.13 oligodendrocyte cultures. MO3.13 cultures maintained in growth medium show expression of myelin basic protein (MBP, in green) and glial fibrillary acidic protein (GFAP red) (A). TOPRO3, a nuclear stain, appears blue. Upon differentiation, when growth medium is replaced with differentiation medium, cells change in morphology, continue to show expression of MBP, and the expression of GFAP is decreased (B).