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Figure 6 | Journal of Neuroinflammation

Figure 6

From: A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi

Figure 6

B. burgdorferi induces elevated levels of activated caspase-3 in differentiated MO3.13 cells. Flow cytometric evaluation of activated caspase-3 in differentiated MO3.13 cells following incubation in differentiation medium (top panel) and with live B. burgdorferi (MOI, 10:1) for 48 h (bottom panel). The mean percent of MBP-positive cells showing positive staining for activated caspase-3 in cultures held in medium (0.18 ± 0.1) was elevated by 30-fold in MO3.13 cells incubated with live B. burgdorferi (5.45 ± 0.48). The figure shows the results of two independent experiments.

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Journal of Neuroinflammation

ISSN: 1742-2094