Etiology of autistic features: the persisting neurotoxic effects of propionic acid

Table 3 Mean ± SEM and percentage change of selective short-chain and long-chain polyunsaturated fatty acids (LC-PUFA) in the brain homogenates of the two groups of rats. Significant level at p <0.05

Fatty acid	Groups	Control	PA	Pvalue
Acetic	Mean ± SEM	0.02 ± 0.003	0.07 ± 0.007	0.001
	%change	100.00	455.44
PA	Mean ± SEM	0.01 ± 0.003	0.13 ± 0.01
	%change	100.00	1051.32
18:2-n6 Linoleic	Mean ± SEM	2.64 ± 0.1	1.79 ± 0.1
	%change	100.00	74.88
18:3-n6 γ-linolenic	Mean ± SEM	1.33 ± 0.06	1.11 ± 0.056	0.065
	%change	100.00	83.15
AA	Mean ± SEM	0.56 ± 0.028	0.35 ± 0.021	0.004
	%change	100.00	61.89
EPA	Mean ± SEM	0.34 ± 0.04	0.16 ± 0.025
	%change	100.00	47.38
22:5-n3 Docosapentaenoic (clupanodonic)	Mean ± SEM	1.01 ± 0.07	0.46 ± 0.025
	%change	100.00	45.05	<0.001
22:5-n6 Docosapentaenoic (Osbond)	Mean ± SEM	1.33 ± 0.16	0.93 ± 0.067
	%change	100.00	69.98
DHA	Mean ± SEM	0.4 ± 0.05	0.16 ± 0.007
	% change	100.00	40.2

AA arachidonic acid; DHA docosahexanoic acid; EPA eicosapentaenoic acid; PA propionic acid; SEM standard error of the mean.

ISSN: 1742-2094