Table 8 ROC analysis of measured parameters in the PA-treated group of rats
From: Etiology of autistic features: the persisting neurotoxic effects of propionic acid
Parameter | Area under the curve | Cutoff value | Sensitivity % | Specificity % |
|---|---|---|---|---|
GSH (μg/ml) | 0.844 | 70.12 | 100.0% | 25.0% |
GPX (U/100 mg) | 1.000 | 6.03 | 100.0% | 20.0% |
MD | 0.984 | 0.09 | 87.5% | 87.5% |
Vitamin C levels in brain | 0.944 | 24.23 | 100.0% | 16.7% |
Catalase | 0.688 | 5.36 | 85.7% | 12.5% |
CK (U/L) | 1.000 | 79.32 | 100.0% | 80.0% |
LDH (umoles/L) | 0.944 | 2431.78 | 100.0% | 16.7% |
Acetic acid | 1.000 | 0.02 | 100.0% | 40.0% |
PA | 1.000 | 0.02 | 100.0% | 80.0% |
18:2-n6 (Linoleic) | 0.959 | 2.92 | 100.0% | 14.3% |
18:3-n6 (γ -linolenic) | 0.847 | 1.51 | 100.0% | 14.3% |
AA | 1.000 | 0.64 | 100.0% | 14.3% |
EPA | 1.000 | 0.665 | 100.0% | 100% |
22:5-n3 Docosapentaenoic (clupanodonic) | 1.000 | 0.635 | 100.0% | 100% |
22:5-n6 Docosapentaenoic (Osbond) | 0.959 | 1.49 | 100.0% | 14.3% |
DHA | 1.000 | 0.44 | 100.0% | 14.3% |
PE | 1.000 | 0.19 | 100.0% | 25.0% |
PS | 1.000 | 0.34 | 100.0% | 25.0% |
PC | 1.000 | 4.89 | 100.0% | 25.0% |
Caspase3 | 1.000 | 125.45 | 100.0% | 75.0% |
IL-6 | 0.917 | 136.48 | 66.7% | 75.0% |
TNFα | 1.000 | 125.03 | 100.0% | 100.0% |
INFγ | 1.000 | 95.15 | 100.0% | 80.0% |
HSP70 | 1.000 | 35.19 | 100.0% | 80.0% |
GABA | 1.000 | 93.025 | 100.0% | 100.0% |
Serotonin | 0.944 | 8.19 | 100.0% | 100% |
Dopamine | 0.972 | 19.69 | 100.0% | 25.0% |
Adrenaline | 1.000 | 6.65 | 100.0% | 33.3% |
Noradrenaline | 1.000 | 5.13 | 100.0% | 33.3% |
Tailed% | 1.000 | 4.70 | 100.0% | 66.7% |
Tail length (μm) | 1.000 | 1.18 | 100.0% | 66.7% |
Tail moment | 1.000 | 1.51 | 100.0% | 66.7% |