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Table 8 ROC analysis of measured parameters in the PA-treated group of rats

From: Etiology of autistic features: the persisting neurotoxic effects of propionic acid

Parameter Area under the curve Cutoff value Sensitivity % Specificity %
GSH (μg/ml) 0.844 70.12 100.0% 25.0%
GPX (U/100 mg) 1.000 6.03 100.0% 20.0%
MD 0.984 0.09 87.5% 87.5%
Vitamin C levels in brain 0.944 24.23 100.0% 16.7%
Catalase 0.688 5.36 85.7% 12.5%
CK (U/L) 1.000 79.32 100.0% 80.0%
LDH (umoles/L) 0.944 2431.78 100.0% 16.7%
Acetic acid 1.000 0.02 100.0% 40.0%
PA 1.000 0.02 100.0% 80.0%
18:2-n6 (Linoleic) 0.959 2.92 100.0% 14.3%
18:3-n6 (γ -linolenic) 0.847 1.51 100.0% 14.3%
AA 1.000 0.64 100.0% 14.3%
EPA 1.000 0.665 100.0% 100%
22:5-n3 Docosapentaenoic (clupanodonic) 1.000 0.635 100.0% 100%
22:5-n6 Docosapentaenoic (Osbond) 0.959 1.49 100.0% 14.3%
DHA 1.000 0.44 100.0% 14.3%
PE 1.000 0.19 100.0% 25.0%
PS 1.000 0.34 100.0% 25.0%
PC 1.000 4.89 100.0% 25.0%
Caspase3 1.000 125.45 100.0% 75.0%
IL-6 0.917 136.48 66.7% 75.0%
TNFα 1.000 125.03 100.0% 100.0%
INFγ 1.000 95.15 100.0% 80.0%
HSP70 1.000 35.19 100.0% 80.0%
GABA 1.000 93.025 100.0% 100.0%
Serotonin 0.944 8.19 100.0% 100%
Dopamine 0.972 19.69 100.0% 25.0%
Adrenaline 1.000 6.65 100.0% 33.3%
Noradrenaline 1.000 5.13 100.0% 33.3%
Tailed% 1.000 4.70 100.0% 66.7%
Tail length (μm) 1.000 1.18 100.0% 66.7%
Tail moment 1.000 1.51 100.0% 66.7%
  1. AA arachidonic acid; CK creatine kinase; DHA docosahexanoic acid; EPA eicosapentaenoic acid; GABA gamma aminobutyric acid; GPX glutathione peroxidase; GSH glutathione; LDH lactate dehydrogenase; MD malondialdehyde; PA propionic acid; PC phosphatidylcholine; PE phosphatidylethanolamine; PS phosphatidylserine; ROC receiver operating characteristics.