The specific inducible nitric oxide synthase (iNOS) inhibitor
-(3-(aminomethyl)benzyl)acetamidine (1400 W) abrogated the increase of iNOS mRNA expression induced by unpredictable chronic mild stress (UCMS) in the cortex. UCMS-exposed mice were subjected to various stressors for 4 weeks. Transcript of iNOS was assayed by RT-PCR in the cortex. Values are mean ± SEM (n = 4 in each group). **
P <0.01 for each comparison.