The specific inducible nitric oxide synthase (iNOS) inhibitor
-(3-(aminomethyl)benzyl)acetamidine (1400 W) abrogated the increase of nitrite, a stable NO product. Mice were subjected to various stressors in the presence or absence of the iNOS inhibitor 1400 W for 4 weeks. Nitrite was assayed by Griess reagent. Data are mean ± SEM (n = 6 for control; n = 6 for stress; n = 5 for stress + 1400 W). **
P <0.01 for each comparison.