The specific inducible nitric oxide synthase (iNOS) inhibitor
-(3-(aminomethyl)benzyl)acetamidine (1400 W) abrogated the decrease of sucrose preference induced by unpredictable chronic mild stress (UCMS). Mice were subjected to various stressors in the presence or absence of the iNOS inhibitor 1400 W for 4 weeks. Sucrose preference = sucrose consumption/(sucrose consumption + water consumption) × 100%. Data are mean ± SEM (n = 7 for control; n = 6 for stress; n = 9 for stress + 1400 W). *
P <0.05 for each comparison.