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Table 1 Summary of genes most strongly regulated by lesion only or SRF-VP16

From: Serum response factor modulates neuron survival during peripheral axon injury

  Lesion-specific genes SRF-VP16-specific genes
  Gene name Gene symbol Up Gene name Gene symbol Up
1 Small proline-rich protein 2J Sprr2j 80.1 Actin, alpha, cardiac Actc1 13.2
2 G protein-coupled receptor 151 Gpr151 31.0 Protein phosphatase with EF hand Ppef1 12.2
3 Activating transcription factor 3 Atf3 28.6 Tissue inhibitor of metalloprot. 1 Timp1 12.2
4 Glutamate receptor, metab. 3 Grm3 24.9 Ankyrin repeat domain 1 Ankrd1 10.3
5 Protein phosphatase with EF Ppef1 19.9 Calponin 1 Cnn1 9.5
6 Galanin Gal 19.8 Coagulation factor II receptor-like 2 F2rl2 8.7
7 Tissue inhibitor of metalloprot. 1 Timp1 14.3 Actin, alpha 2, smooth muscle Acta2 7.9
8 Neuropeptide Y Npy 13.2 Transgelin (Sm22) Tagln 6.4
9 Annexin a10 Anxa10 12.7 Apolipoprotein L 7b | L 7e Apol7b/e 4.7
10 Small proline-rich protein 2 J Sprr2j 12.7 Serine (or cysteine) peptidase inh. Serpine1 4.5
11 Tubulin, beta 6 Tubb6 11.4 T-box18 Tbx18 3.8
12 Ankyrin repeat domain 1 Ankrd1 11.4 Interleukin 1 receptor, type II Il1r2 3.8
13 Wingless related 2b Wnt2b 10.6 Actinin alpha 3 Actn3 3.7
14 A disintegrin and metallopept. 8 Adam8 9.5 Angiopoietin-like 2 Angptl2 3.4
15 S100 calcium binding prot. A11 S100a11 9.2 Insulin-like growth fac. bind. prot. 6 Igfbp6 3.2
16 Xanthine dehydrogenase Xdh 8.7 Follistatin Fst 3.2
17 Anthrax toxin receptor 2 Antxr2 8.5 GLI pathogenesis-related 1 Glipr1 3.1
18 SH2 domain protein 1B2 Sh2d1b2 8.4 Solute carrier family 38, member 8 Slc38a8 2.9
19 Gastrin releasing peptide Grp 7.5 Early growth response 1 Egr1 2.7
20 Vasoactive intestinal polypeptide Vip 7.4 Dihydroxyacetone kinase 2 hom. Dak 2.7
21 Protein C receptor, endothelial Procr 6.9 Tuftelin 1 Tuft1 2.6
22 Integrin alpha 7 Itga7 6.8 Serum response factor Srf 2.4
23 Lymphocyte antigen 86 Ly86 6.8 Bone marrow stromal cell antigen 1 Bst1 2.4
24 Nerve growth factor Ngf 6.5 Dopamine receptor 2 Drd2 2.4
25 Integrin alpha M Itgam 6.1 Desmocollin 3 Dsc3 2.3
26 Prokineticin receptor 2 Prokr2 6.0 Blood vessel epicardial substance Bves 2.2
27 Serine (or cysteine) pept. inh. Serpine1 5.9 ALX homeobox 1 Alx1 2.2
28 G protein-coupled receptor 133 Gpr133 5.7 Neuronal pentraxin 2 Nptx2 2.2
29 Cyclin-dep. kinase inh.1A (P21) Cdkn1a 5.6 Glucagon-like peptide 1 receptor Glp1r 1.9
30 GalaninCD180 antigen Cd180 5.4 Regulator of G-protein signaling 4 Rgs4 1.7