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Figure 5 | Journal of Neuroinflammation

Figure 5

From: The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation

Figure 5

URB597 treatment increased concentrations of the endocannabinoid AEA and the N -acylethanolamines OEA and PEA. Analysis of the analyte concentrations revealed a significant treatment effect for AEA (F(1,23) = 6.29, +P < 0.05; #P < 0.05; 2-way ANOVA; a), OEA (F(1,23) = 35.30, +++ P < 0.001; ### P < 0.001; b) and PEA (F(1,23) = 29.21, +++ P < 0.001; ### P < 0.001; c) and a significant age x treatment interaction was observed in the case of 2-AG (F(1,23) = 4.86, **P < 0.01; d).

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