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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice

Figure 4

Microglial cell density was increased in Tg APP and decreased by continuous JWH oral treatment. A: representative Iba-1 immunostaining in cerebral cortex following the different treatments. B: microglial cortical cell density. Animals were treated with vehicle or cannabinoids (0.2 mg/kg) in the drinking water for 4 months, starting at 7 months of age. Results are mean ± SEM (n = 6-7 mice/group). #p < 0.05 vs wild type vehicle treated mice; * p < 0.05 vs Tg APP vehicle treated mice (ANOVA followed by Student's t test).

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Journal of Neuroinflammation

ISSN: 1742-2094