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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Preventive immunization of aged and juvenile non-human primates to beta-amyloid

Figure 4

Aβ composition in primate brains. (A) Western blot analysis of Aβ oligomers in the membrane fraction of brain extracts from immunized (n = 10) and non-immunized aged non-human-primates (n = 6) using 6E10 antibody. The left lanes show human brain tissue samples without Alzheimer’s disease (AD), with mild cognitive impairment, and with AD for comparison. (B) Densitometric analysis showed a significant difference in the dimer to pentamer ratio in immunized compared with non-immunized aged animals. Bars represent mean ± SD.

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