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Table 2 Baseline Aβ 40 , Aβ 42 and total tau levels in cerebrospinal fluid and plasma of juvenile and aged NHPs (median and interquartile range)

From: Preventive immunization of aged and juvenile non-human primates to beta-amyloid

  Juvenile animals (n = 19) Aged animals (n = 16) P -value
Cerebrospinal fluid
  Aβ40, pg/ml 1494 (923 to 2077) 1514 (971 to 2145) NS
  Aβ42, pg/ml 78.4 (65.3 to 118.4) 107.4 (59.8 to 162.1) NS
  Tau, pg/ml 131.4 (89.4 to 168.2) 249.0 (94.2 to 345.2) 0.06
  Tau/Aβ42 1.48 (0.84 to 1.94) 1.84 (1.20 to 3.40) NS
Plasma
  Aβ40, pg/ml 16.0 (15.1 to 21.0) 15.1 (11.4 to 18.8) NS
  Aβ42, pg/ml ND ND  
  1. ND, not detected; NS, not significant.