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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway

Figure 1

Circadian sleep characteristics and sleep state distribution during baseline conditions (solid line) and after 15 days of sleep fragmentation (dotted line) in mice. (A–C) There was an absence of significant alterations in sleep architecture, despite (D) continuing successful induction of episodic awakenings. (E) No changes in delta frequency power of the EEG emerged; but there were (F) marked reductions in mean sleep latency. (BL) baseline vs. sleep fragmentation (SF); *P < 0.0001; n = 12/group). Shaded regions represent dark phase of the circadian cycle (07.00 to 19.00 hours).

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