The effects of nicotine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse motor deficits. Pole-test scores for each animal were calculated after acute MPTP treatment at 3 hours, 1 day, 2 days and 7 days. Data are presented as mean ± SEM (n = 10). *P < 0.05 and **P < 0.01 versus the control (saline alone) group; #
P < 0.05 and ##
P < 0.01 versus the MPTP treatment group.