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Figure 4 | Journal of Neuroinflammation

Figure 4

From: α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation

Figure 4

The effects of nicotine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced microglia activation in the mouse substantia nigra pars compacta (SNpc). (A) Mac-1-IR microglia in mouse SNpc. Scale bar: 200 μm. (B) Stereological cell counts of Mac-1-IR microglia in the mouse SNpc. Data are presented as a percentage of controls (mean ± SEM) from four to six mice per group. *P < 0.05 and **P < 0.01 versus the control (saline-only) group; ## P < 0.01 versus the MPTP treatment group.

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Journal of Neuroinflammation

ISSN: 1742-2094