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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice

Figure 5

Ultrastructure of cortex and hippocampus in 12-month old APPswePS1dE9 mice. Transmission electron microscopy (TEM) cortical (A) and hippocampal (C) representative images (n = 3 mice) showed dystrophic neurites (marked by *) with a large accumulation of autophagic vesicles (AVs). (B) represents a magnified region of interest (defined by a white square in image (a)) within many AVs with a dense compacted amorphous or multilamellar content as indicated by white arrows.

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