Figure 4

Phenotyping of MHC II ⁺ seven days after tMCAO. Number of MHC II⁺ cells in total in the ipsilateral (A) and contralateral (B) hemisphere. Data are presented as means ± SEM and a ratio between the number of MHC II⁺ cells to the total number of cells. Number of MHC II⁺ cells co-expressing (CD11b⁺CD45⁺), defined as microglia/macrophages in the ipsilateral (C) and contralateral (D) hemisphere presented as means ± SEM and as a ratio of CD11b⁺CD45⁺ cells to the total number of MHC II⁺ cells. Number of MHC II⁺ cells co-expressing CD11b⁺CD11c⁺CD45⁺, defined as myeloid dendritic cells in the ipsilateral (E) and contralateral (F) hemisphere presented as means ± SEM and as a ratio of CD11b⁺CD11c⁺CD45⁺ cells to the total number of MHC II⁺ cells. Co-expression of stimulatory molecules, CD86 in the ipsilateral (G) and contralateral hemisphere (H) and CD80 in the ipsilateral (I) and contralateral hemisphere (J) presented as means ± SEM and as ratio to the total number of MHC II⁺ cells. Abbreviations: VH, vehicle; LD, levodopa/benserazide; Ipsi, ipsilateral hemisphere; Contra, contralateral hemisphere.