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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro

Figure 1

CNPase immunofluorescence was increased in the brain in postnatal rats following lipopolysaccharide injection. Confocal images showing the distribution of lectin (green), CNPase (red) and DAPI (blue) immunoreactive cells in the postnatal rat brain at 1 (d-f), 3 (g-i) and 6 hours (j-l) after lipopolysaccharide (LPS) treatment and the corresponding control (a-c). Colocalized expression of CNPase in lectin immunoreactive cells (arrows in c, f, i, l) can be seen. Note the upregulated expression of CNPase in some lectin-positive microglial cells after LPS treatment (f, i, l,). Arrows indicate microglial cells expressing both lectin and CNPase. Scale bar= = 20 μm (A). CNPase, 2′,3′-cyclic nucleotide 3′-phosphodiesterase; DAPI, 4′,6- diamidino-2-phenylindole.

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Journal of Neuroinflammation

ISSN: 1742-2094