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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis

Figure 3

Cellular immune responses specific to different tau proteins were detected in rTg4510 mice following immunizations with wild-type (Wt)- or P301L-tau proteins. (A) Proliferation of T cells is detected by [3H]-thymidine incorporation assay in splenocyte cultures obtained from experimental and control animals and expressed as stimulation index. (B) Number of IFN-γ producing cells (spot formatting cells, SFC) is detected by ELISPOT assay in splenocyte cultures obtained from immunized rTg4510 mice. Bars represent average ± SD (n = 4).

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