Figure 7

CD4 ⁺ T-cells in the mouse brain after hypoxia-ischemia (HI) in postnatal day (PND) 5 mice. The total number of CD4⁺ cells in blood vessels and in tissue from both of the brain hemispheres from a section at the hippocampus level (A) and spleen weight (B) in uninjured control (Cont) mice versus HI mice at different time points after HI. *P < 0.05, **P < 0.01, ***P < 0.001 using Student's unpaired t-test. Data are presented as mean ± SEM. (C and D) Representative immunostainings show CD4⁺ cells in blood vessels in the ipsilateral subcortical white matter (C) and ipsilateral hippocampus CA1 area (D) at seven days post-HI.