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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain hypersensitivity in a rat model of peripheral nerve injury

Figure 3

Mechanical and thermal hypersensitivity after partial sciatic nerve ligation. Rats were tested for mechanical hypersensitivity (A-C) by using von Frey filaments, and for thermal hypersensitivity (D-E) with the thermal paw stimulator during 20 days after partial sciatic nerve ligation (PSNL) surgery. Paw withdrawal threshold (PWT) of the ipsilateral (A) or contralateral (B) hindpaws after mechanical stimulation are expressed as percentage of the baseline PWT. Paw withdrawal latencies (PWL) of the ipsilateral (D) or contralateral (E) hindpaws after thermal stimulation are expressed as percentage of the baseline PWL. (C,F) Area under the curve (AUC) analysis of the corresponding graphs. Data shown are mean values with SEM. For AUC: *P < 0.05, *** P < 0.001, analysed by two-tailed student’s t-test. Day-by-day differences between groups were calculated by whole sample t-tests with * at least P < 0.05. Each group consisted of 9 to 11 animals.

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Journal of Neuroinflammation

ISSN: 1742-2094