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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures

Figure 6

Detection of anti-Hu antibody induced apoptotic neuronal death using FLICA staining as compared with TUNEL staining. The top two panels show terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) negative and positive controls (see Methods). In the bottom panels arrows indicate the same neurons showing fluorochrome-labeled inhibitors of caspases (FLICA) or TUNEL staining (blue), containing immunoglobulin (Ig)G (red), or in merged images showing both IgG and FLICA or TUNEL staining (pink). Magnification bar = 20 μm.

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Journal of Neuroinflammation

ISSN: 1742-2094