Figure 1
From: Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function
Low testosterone and high-fat diet increases metabolic indices. (A) Graphical representation of the percentage differences in average body weight of animals in sham GDX (Sham), GDX, and GDX mice with testosterone treatment (GDX + T) in both control-diet and high-fat diet. (B, C). Graphical representations of average fasting blood glucose and insulin in each treated group. ((D) Graphical representation of HOMA index, which is representative of level of insulin resistance in each group. (E) Graphical representation of area under the curve (AUC) for glucose tolerance test (0 to 120 min) from each group of animals. Statistical significance is based on ANOVA followed by Bonferroni. * P ≤0.05 between the diet groups; ** P ≤0.05 between hormone groups; N ≥6.