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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation

Figure 3

Effect of bilobalide on brain water content. Pretreatment with bilobalide (5, 10 mg/kg) significantly reduced brain water content in the ipsilateral hemisphere, but did not affect brain water content in the contralateral hemisphere compared with the MCAO/R group. Mean values ± standard error of the mean for six rats per group. * P < 0.05, ** P < 0.01 versus sham; # P < 0.05, ## P < 0.01 versus MCAO/R. BB, bilobalide; MCAO/R, middle cerebral artery occlusion and reperfusion; NMP, nimodipine.

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