Figure 1

Hormone and autoantibody levels. (A) There was no significant difference in average 17β-estradiol level between the MRL/lpr WT and MRL/lpr ERαKO groups of mice. (B) There was also no correlation between individual serum estradiol levels and behavior (performance in the WRAM). (C) There was no significant difference between MRL/lpr WT and ERαKO mice with regard to anti-dsDNA levels at 10 weeks of age. POS = single sample from a sick/aged MRL/lpr WT; NEG = single sample from a B6 mouse.