Skip to main content
Figure 3 | Journal of Neuroinflammation

Figure 3

From: Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis

Figure 3

Validation of apolipoprotein AI, semaphorin 7A, and ala-beta-his-dipeptidase as biomarkers associated with conversion to CDMS in a second and totally independent cohort of CIS patients. Boxplots depicting CSF levels of apolipoprotein AI determined by ELISA, and CSF abundance of CNDP1 and semaphorin 7A determined by selected reaction monitoring in MS converters and non-converters to MS. Statistically significant P values are shown in bold. *Indicates that significant differences were also observed between CIS → CDMS and controls (P = 2.9 × 10-3). CIS → CIS: CIS patients who did not convert to clinically definite MS during the follow-up period. CIS → CDMS: CIS patients who converted to clinically definite MS. C: controls with other neurological disorders. Numbers in parentheses indicate individuals available for analysis. CDMS, clinically definite multiple sclerosis; CDNP1, ala-beta-his-dipeptidase; CIS, clinically isolated syndromes, CSF, cerebrospinal fluid.

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094