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Table 1 Morphological characteristics of forebrain microglia

From: Quantitative assessment of microglial morphology and density reveals remarkable consistency in the distribution and morphology of cells within the healthy prefrontal cortex of the rat

 

Layer I

Layer II

Layer III

Layer V

Layer VI

Fractal dimension (k-dim)

0.992 (0.008)

0.980 (0.009)

0.996 (0.006)

0.989 (0.005)

0.990 (0.006)

Convex hull area (ÎĽm2)

1,605.52 (88.36)

1,818.78 (95.61)

1,761.14 (71.11)

1,634.34 (68.87)

1,577.00 (56.40)

Cell body perimeter (ÎĽm)

34.43 (0.98)

33.81 (1.13)

34.57 (1.49)

30.58 (0.73)

31.61 (1.34)

Branch points

10.81 (0.60)

10.59 (0.54)

11.98 (0.61)

11.02 (0.63)

11.87 (0.64)

Total process length (ÎĽm)

243.72 (12.44)

257.63 (12.81)

274.69 (11.21)

251.19 (10.55)

261.10 (10.19)

Total process volume (ÎĽm3)

54.13 (4.68)

55.49 (4.32)

55.37 (3.56)

53.17 (3.33)

54.93 (3.76)

Number of processes

4.51 (0.16)

4.39* (0.19)

5.15 (0.20)

5.16 (0.17)

5.0 (0.16)

  1. Microglia from each cortical layer were assessed for size and complexity of branch structure using computer-generated cell reconstructions. Values are expressed as mean (± standard error of the mean); *P <0.05 compared with Layers III and V.