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Table 1 Assessment of physiological parameters in saline-, XPro1595- and etanercept-treated mice after focal cerebral ischemia

From: Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

Time point Sham Saline XPro1595 Etanercept
Weight ( Δg )
D0 0.69 ± 0.15 0.48 ± 0.16 0.41 ± 0.14 0.45 ± 0.17
D1 0.19 ± 0.17 0.16 ± 0.20 0.12 ± 0.24 0.11 ± 0.21
D3 ****-0.61 ± 0.20 ****-0.79 ± 0.22 ****-0.89 ± 0.15 ****-0.81 ± 0.14
D5 *0.14 ± 0.27 **0.11 ± 0.18 **-0.12 ± 0.22 **-0.14 ± 0.29
Temperature C )
BL 32.69 ± 0.49 32.21 ± 0.38 31.95 ± 0.32 32.41 ± 0.35
30 min after pMCAO ***27.28 ± 0.22 ***27.37 ± 0.22 ***27.52 ± 0.15 ***27.41 ± 0.21
3 h after pMCAO ***27.15 ± 0.32 ***26.89 ± 0.27 ***26.51 ± 0.30 ***26.59 ± 0.28
  1. BL, baseline. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 (two-way repeated measures ANOVA).