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Table 1 Assessment of physiological parameters in saline-, XPro1595- and etanercept-treated mice after focal cerebral ischemia

From: Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

Time point

Sham

Saline

XPro1595

Etanercept

Weight ( Δg )

D0

0.69 ± 0.15

0.48 ± 0.16

0.41 ± 0.14

0.45 ± 0.17

D1

0.19 ± 0.17

0.16 ± 0.20

0.12 ± 0.24

0.11 ± 0.21

D3

****-0.61 ± 0.20

****-0.79 ± 0.22

****-0.89 ± 0.15

****-0.81 ± 0.14

D5

*0.14 ± 0.27

**0.11 ± 0.18

**-0.12 ± 0.22

**-0.14 ± 0.29

Temperature C )

BL

32.69 ± 0.49

32.21 ± 0.38

31.95 ± 0.32

32.41 ± 0.35

30 min after pMCAO

***27.28 ± 0.22

***27.37 ± 0.22

***27.52 ± 0.15

***27.41 ± 0.21

3 h after pMCAO

***27.15 ± 0.32

***26.89 ± 0.27

***26.51 ± 0.30

***26.59 ± 0.28

  1. BL, baseline. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 (two-way repeated measures ANOVA).