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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

Figure 5

Effect of IDO inhibition on immune induced QUIN toxicity. The schematic bar diagram represents the effect of berberine, D-1MT, L-1MT and DL-1MT (0 to 4 μM) on IFN-γ-treated BV2 supernatant in N19 (a) and N20.1 (b) oligodendroglial cell lines. The levels of lactate dehydrogenase (LDH) released by oligodendroglial cell lines after 72 hours incubation with IFN-γ-treated BV2 supernatant. The study was performed in triplicate and the error bars indicate SE. ***P < 0.001.

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