Figure 3
From: Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia
Perfect overlay of the binding pattern observed with patient IgG and that observed with a commercial antibody to ITPR1, a well-established specific marker of Purkinje cells (PCs). Anti-ITPR1 reactivity is depicted in red (Alexa Fluor® 568), the patient antibody in green (Alexa Fluor® 488), and yellow indicates overlay of the two antibodies. Nuclei are shown in blue (DAPI).