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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice

Figure 2

Vitamin D3 pre-treatment did not modulate bacterial loads and did not influence meningeal inflammation during meningoencephalitis. Bacterial concentrations in (A) the cerebellum and (B) the spleen at the end stage of infection in animals that were killed or died during the acute phase of infection and (C) in the cerebellum, and (D) the spleen 20 h after intracerebral E. coli K1 infection. (E) The mean numbers of chloroacetate-esterase-stained leukocytes per area in brain sections of mice fed a diet containing different amounts of vitamin D (low (L-VitD), standard (S-VitD) or high (H-VitD) vitamin D supplementation), which were killed after 20 h of E. coli meningoencephalitis (n ≥ 15). Bars indicate mean and standard deviation (SD). Statistical analysis was performed by one-way ANOVA followed by Bonferroni correction for multiple comparisons. (A,B) n ≥ 8, (C,D,E) n ≥15 mice per group.

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