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Figure 3 | Journal of Neuroinflammation

Figure 3

From: TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain

Figure 3

TNF-α up-regulation, and apoptosis of endothelial cells, neurons, and oligodendrocyte progenitors after lipopolysaccharide (LPS)-sensitized hypoxic-ischemia (HI). Immunofluorescence in the LPS + HI group 24 hours post-insult showed that many Iba1-positive activated microglia co-expressed TNF-α, whereas IB4-positive endothelial cells, NeuN-positive neurons, and O4-postive oligodendrocytes precursor cells co-expressed cleaved caspase-3. Scale bar = 50 μm for IB4 and 25 μm for others. Inset scale bar = 5 μm.

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Journal of Neuroinflammation

ISSN: 1742-2094