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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus

Figure 4

The pretreatment of ouabain (OUA) (1.8 μg/ kg) on lipopolysaccharide (LPS)-induced (200 μg /kg) astrocyte activation. Astrocyte activity was measure with glial fibrillary acidic protein (GFAP) immunofluorescence in the dentate gyrus. (A) Representative photomicrographs showed that LPS increases astrocytic activation, with OUA pretreatment reducing this. The arrow represents an activated astrocyte. (B) Densitometric analysis of the % of GFAP-positive cells/total cells. *P < 0.05 versus control, OUA and OUA + LPS. Data are presented as mean ± SEM from five individual experiments. One-way ANOVA followed by Newman-Keuls post-test.

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