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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus

Figure 6

Effects of ouabain (OUA) pretreatment (1.8 μg/ kg) on lipopolysaccharide (LPS)-induced (200 μg/ kg) regulation of hippocampal brain-derived neurotrophic factor (BDNF) and TNF-α levels. (A) The levels of BDNF were decreased in LPS and OUA groups in comparison with control and OUA + LPS group, a P < 0.05 versus control and LPS and b P < 0.01 versus control and OUA + LPS and P < 0.05 versus OUA. (B) The levels of TNF-α in the hippocampus, a P < 0.01 versus control and OUA + LPS and b P < 0.05 versus control and OUA + LPS. Data are presented as mean ± SEM from five individual experiments. One-way ANOVA followed by Newman-Keuls test.

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