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Table 3 Differential blood count, flow cytometric and RT-PCR results of patient subgroups

From: Anti-inflammatory T-cell shift in neuropathic pain

Item Healthy NeP (all) PNeP PHN OFP
Neutrophils (%) 55.4 ± 9.1 58.6 ± 9.3 57.5 ± 10.1 57.3 ± 9.0 62.3 ± 8.5
Lymphocytes (%) 33.8 ± 8.1 29.2 ± 8.2 30.5 ± 7.9 28.3 ± 9.6 27.2 ± 8.1
CD4+ Counts × 1000 28.7 ± 7.3 33.5 ± 15.4 36.8 ± 18.8 30.3 ± 15.3 30.8 ± 2.9
CD4+ (%) 43.4 ± 9.9 47.5 ± 11.9 49.9 ± 12.6 44.3 ± 13.8 46.6 ± 8.0
TH1 (%) 9.7 ± 4.7 9.6 ± 4.1 10.9 ± 4.7 7.2 ± 3.1 9.3 ± 2.7
TH2 (%) 1.3 ± 1.2 1.5 ± 0.8 1.7 ± 0.7 0.9 ± 0.5 2.0 ± 0.9
TH17 (%) 1.3 ± 1.0 0.7 ± 0.4* 0.9 ± 0.4 0.4 ± 0.1* 0.8 ± 0.5
RORγT 2.7 ± 1.4 1.9 ± 1.0 1.8 ± 0.6* 1.9 ± 1.2* 2.2 ± 1.5
CD4+CD25high (%) 3.7 ± 0.7 5.4 ± 1.5* 5.1 ± 1.8* 5.0 ± 0.7* 6.4 ± 0.9*
Tregs (%) 2.0 ± 1.0 3.9 ± 1.3* 3.5 ± 1.1* 4.0 ± 1.9* 4.4 ± 0.9*
FoxP3 0.6 ± 0.2 1.2 ± 0.8* 1.0 ± 0.7* 1.3 ± 0.3* 1.4 ± 1.3*
  1. NeP (all): all patients suffering from neuropathic pain; PNeP: Peripheral neuropathic pain (symmetrical polyneuropathy/peripheral mononeuropathy); PHN: postherpetic neuralgia; OFP: orofacial pain; Results are expressed as mean ± standard deviation (SD), *P <0.05 versus healthy controls.