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Table 3 Differential blood count, flow cytometric and RT-PCR results of patient subgroups

From: Anti-inflammatory T-cell shift in neuropathic pain

Item

Healthy

NeP (all)

PNeP

PHN

OFP

Neutrophils (%)

55.4 ± 9.1

58.6 ± 9.3

57.5 ± 10.1

57.3 ± 9.0

62.3 ± 8.5

Lymphocytes (%)

33.8 ± 8.1

29.2 ± 8.2

30.5 ± 7.9

28.3 ± 9.6

27.2 ± 8.1

CD4+ Counts × 1000

28.7 ± 7.3

33.5 ± 15.4

36.8 ± 18.8

30.3 ± 15.3

30.8 ± 2.9

CD4+ (%)

43.4 ± 9.9

47.5 ± 11.9

49.9 ± 12.6

44.3 ± 13.8

46.6 ± 8.0

TH1 (%)

9.7 ± 4.7

9.6 ± 4.1

10.9 ± 4.7

7.2 ± 3.1

9.3 ± 2.7

TH2 (%)

1.3 ± 1.2

1.5 ± 0.8

1.7 ± 0.7

0.9 ± 0.5

2.0 ± 0.9

TH17 (%)

1.3 ± 1.0

0.7 ± 0.4*

0.9 ± 0.4

0.4 ± 0.1*

0.8 ± 0.5

RORγT

2.7 ± 1.4

1.9 ± 1.0

1.8 ± 0.6*

1.9 ± 1.2*

2.2 ± 1.5

CD4+CD25high (%)

3.7 ± 0.7

5.4 ± 1.5*

5.1 ± 1.8*

5.0 ± 0.7*

6.4 ± 0.9*

Tregs (%)

2.0 ± 1.0

3.9 ± 1.3*

3.5 ± 1.1*

4.0 ± 1.9*

4.4 ± 0.9*

FoxP3

0.6 ± 0.2

1.2 ± 0.8*

1.0 ± 0.7*

1.3 ± 0.3*

1.4 ± 1.3*

  1. NeP (all): all patients suffering from neuropathic pain; PNeP: Peripheral neuropathic pain (symmetrical polyneuropathy/peripheral mononeuropathy); PHN: postherpetic neuralgia; OFP: orofacial pain; Results are expressed as mean ± standard deviation (SD), *P <0.05 versus healthy controls.