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Figure 12 | Journal of Neuroinflammation

Figure 12

From: Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia

Figure 12

Scutellarin treatment led to ultrastructural changes of BV-2 microglia. Scanning electron microscopy (SEM) images show that the cells given scutellarin appear flattened with cell bodies that extend numerous processes emitting secondary and tertiary projections. Transmission electron microscopy (TEM) images show that the control BV-2 microglial cells have a relatively round cellular outline. They assume a more ramified phenotype when treated with scutellarin. Parallel arrays of microtubules/microfilaments (arrows) - both in the cell body and in the cytoplasmic processes - are observed after scutellarin treatment.

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Journal of Neuroinflammation

ISSN: 1742-2094