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Figure 3 | Journal of Neuroinflammation

Figure 3

From: In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression

Figure 3

Clinical fundus examination of C57Bl/6 N CD11c-eYFP mice in normal and diseased state. Fundus images of naïve C57Bl/6 N CD11c-eYFP (Crb1 rd8) mice in brightfield (BF) (A) and fluorescent mode (Fluor) (B) displaying multiple retinal lesions and accumulation of CD11c-eYFP+ cells in the retinal lesions attributable to the rd8 mutation. Fundus images of C57Bl/6 N CD11c-eYFP mice (n = 10) immunized with IRBP1–20 on day 14 post-immunization (d14 p.i.) (C-D) and d21 p.i. (E-F) demonstrated perivascular infiltrates. eYFP, enhanced yellow fluorescent protein; rd8, retinal degeneration 8.

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Journal of Neuroinflammation

ISSN: 1742-2094