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Table 2 Experimental autoimmune uveoretinitis clinical grading criteria

From: In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression

Score

Retinal tissue infiltrate

Optic disc

Retinal atrophy

Retinal detachment

Vasculitis

Haemorrhages

Fluorescein leakage

Vitreous haze

0

<5 small lesions

No inflammation

Absent

Absent

Absent

Absent

Absent

Fundus details clearly visible

1

>5 small linear lesions

Minimal inflammation

Absent

Absent

Minimal thickening

Absent

Mild

Fundus details clearly visible

2

>5 medium linear lesions

Mild inflammation

Absent

Absent

Minimal thickening and localised severe thickening

Absent

Moderate

Fundus details clearly visible

3

>5 large linear lesions

Moderate inflammation

Absent

Absent

Localised severe thickening on all vessels or one vessel grossly affected

Present

Severe

Fundus details visible

4

Confluent large linear lesions

Severe inflammation

Present

Present

One or all vessels grossly affected

Present

Severe

Fundus details slightly unclear

5

Confluent large linear lesions

Severe inflammation

Present

Present

One or all vessels grossly affected

Present

Severe

Fundus details not visible