Table 2 Fraction of cerebrospinal (CSF) transcriptome sequences identified by matching IgG peptides in serum and CSF
Total transcriptome sequences recovered | Transcriptome sequences with matching IgG peptides in CSF only | Transcriptome sequences with matching IgG peptides in CSF and serum | Transcriptome sequences with matching IgG peptides in serum only | |||||
|---|---|---|---|---|---|---|---|---|
Subject | Total | AQP4-Specific | Total | AQP4-Specific | Total | AQP4-Specific | Total | AQP4-Specific |
ON10-03 | 15/34 | 6/10 | 14/15 | 6/6 | 1/15 | 0/6 | 0/15 | 0/6 |
(44%) | (60%) | (93%) | (100%) | (7%) | (0%) | (0%) | (0%) | |
ON09-03 | 26/79 | 6/14 | 14/26 | 5/6 | 11/26 | 1/6 | 1/26 | 0/6 |
(33%) | (43%) | (54%) | (83%) | (42%) | (17%) | (4%) | (0%) | |
ON10-01 | 17/106 | 0/9 | 9/17 | NR | 7/17 | NR | 1/17 | NR |
(16%) | (0%) | (53%) | (41%) | (6%) | ||||
ON07-05 | 24/115 | 6/17 | 9/24 | 2/6 | 11/24 | 2/6 | 4/24 | 2/6 |
(21%) | (35%) | (37%) | (33%) | (46%) | (33%) | (17%) | (33%) | |
ON08-08 | 18/49 | 2/3 | 10/18 | 0/3 | 5/18 | 1/2 | 3/18 | 1/2 |
(37%) | (66%) | (55%) | (0%) | (28%) | (50%) | (17%) | (50%) | |
ON11-04 | 13/86 | 2/13 | 1/13 | 0/2 | 3/13 | 1/2 | 9/13 | 1/2 |
(15%) | (15%) | (8%) | (0%) | (23%) | (50%) | (69%) | (50%) | |
TUM09-527 | 11/49 | 6/16 | 8/11 | 5/6 | 1/11 | 0/6 | 2/11 | 1/6 |
(22%) | (38%) | (73%) | (83%) | (9%) | (0%) | (18%) | (17%) | |
Mean | 27% | 37% | 53% | 50% | 28% | 25% | 18% | 19% |
95% CI | 16 to37% | 15 to- 58% | 28 to 78% | 3 to 97% | 13 to 33% | 1 to 49% | 0 to 63% | 0 to 40% |